The distribution of esterase enzymes in Ascaris lumbricoides

Abstract

1. The distribution of non-specific esterase and of cholinesterase in Ascaris lumbricoides has been determined using histochemical methods.2. Non-specific esterase has been shown to be present in the cuticle, in the walls of the excretory canals, in the innervation processes of the muscles, in the coelomocytes, in the oesophageal glands, in the intestine, in the rectal glands, in the male and female reproductive systems, in parts of the nervous system and as 'caps' of enzyme on fat globules in the hypodermis and muscles.3. Cholinesterase has been detected in the innervation processes and sheath of the muscles, in the sphincter muscles, in the intestine, in the sensory papillae and amphids, and in parts of the nervous system, including a nerve in the spicules.4. Parts of the nervous system and the innervation processes of the muscles contain an esterase which is not inhibited by cholinesterase inhibitors and it is suggested that there may be esterase, distinct from cholinesterase, involved in nerve transmission.5. Merocrine secretion of esterase has been observed in the intestine.