Development of Fatty Livers in Fasted Male Mice Bearing a Transplantable Lymphosarcoma.

Abstract

Summary The development of fatty livers has been noted in 8-week-old fasted CBA male mice bearing a transplantable lymphosarcoma of varying age. Similar mice free of the tumor fail to develop fatty livers following a 48-hour fast under comparable conditions, nor does the growth of the tumor in fed mice result in fatty livers. Adrenalectomy has no inhibitory effect on the development of a fatty liver under these conditions.