THE METABOLISM OF INTRAVENOUS TESTOSTERONE BY EXPERIMENTAL ANIMALS1,2
- 30 September 1951
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 49 (4), 467-473
- https://doi.org/10.1210/endo-49-4-467
Abstract
The fate of testosterone admd. intraven. in exptl. animals has been investigated. The injd. hormone diffused rapidly into various tissues of the body, the highest concn. being found in fat. However, within 3 hrs. no measurable amts of testosterone in the fatty tissues. The liver and kidney are both sites of testosterone metabolism in the mammal. That sites other than liver and kidney might be involved in the metabolism of testosterone was indicated by studies in hepatectomized, nephrectomized animals in which less than 50% of the testosterone injd. could be accounted for in most of the tissues.Keywords
This publication has 4 references indexed in Scilit:
- THE STATE AND DISTRIBUTION OF STEROID HORMONES IN BIOLOGIC SYSTEMS .3. SOLUBILITIES OF TESTOSTERONE, PROGESTERONE, AND ALPHA-ESTRADIOL IN AQUEOUS SALT AND PROTEIN SOLUTION AND IN SERUM1948
- METABOLISM OF STEROIDS BY TISSUES .1. DETERMINATION OF TESTOSTERONE AND RELATED STEROIDS IN TISSUE EXTRACTS1947
- METABOLISM OF STEROIDS BY TISSUES .2. THE ENZYMIC DESTRUCTION OF TESTOSTERONE BY LIVER TISSUE1947
- Colorimetric determination of substances containing the grouping —CH2.CO— in urine extracts as an indication of androgen contentBiochemical Journal, 1938