Intradermal 5-Fluorouracil in the Treatment of Basal Cell Carcinoma of the Face

Abstract

The intradermal or infiltrative use of 5-fluorouracil by hypodermic syringe has resulted in the salvage of treatment failures of multifocal basal cell carcinoma of the face. This method is simple and safe, and the initial results have been excellent. It is an effective modality, especially in infiltrating lesions, and it produces little desquamation or side effects and no damage to the surrounding normal skin. Four cases are presented to illustrate how this method has eliminated the need for ablative surgery.