syn-trans Fused Bicyclic Ether Formation via Acetylene-biscobalthexacarbonyl Complex
- 1 June 1996
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 25 (6), 473-474
- https://doi.org/10.1246/cl.1996.473
Abstract
Medium size bicyclic ethers of 7-, 8-, and 9-membered rings were synthesized by connection between a hydroxy group on dihydropyranyl ring and a propargylic cation that was stabilized as an acetylene biscobalthexacarbonyl complex under acidic conditions. This cyclization selectively afforded the syn-trans bicyclic ring system often seen in marine toxins such as ciguatoxin.This publication has 5 references indexed in Scilit:
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