CARBOHYDRATE METABOLISM IN A CASE OF HEMOCHROMATOSIS

Abstract

The progressively increasing severity of the diabetes that occurs with hemochromatosis has been recognized since the earliest description of that disease sixty years ago. The symptoms of diabetes have been the complaints that have forced the majority of patients with hemochromatosis to seek medical advice, and before the advent of insulin, diabetic acidosis was the most frequent cause of death in these patients. Since the use of insulin, the peculiarities of the responses to insulin therapy have been repeatedly noted. In a previous article¹ were reported the clinical and pathologic findings in two cases of hemochromatosis with extensive purpura resembling that of scurvy. One of these (case 2 of the previous report¹) was observed in the hospital for three hundred and seventyone days. It is the purpose in this article to prevent and discuss the course of the diabetes in this case. REPORT OF CASE A widowed, white,