It is our purpose here to point up some of the organizational problems of collaboration which have not been as explicitly set forth as they might in previous discussions of methodology in interdisciplinary work. We feel this is useful because we believe that in the future many of the major advances in knowledge will be made by intellectually and emotionally congenial people from several disciplines who, working together, will cross ordinary academic boundaries in their search for insight. Each of the authors had worked on a number of interdisciplinary projects before collaborating, as anthropologist and psychiatrist, on several current investigations. The thoughts presented here have been stimulated by discussions arising out of this work.