Response of transcortin and α2u-globulin to turpentine-induced inflammation in the rat: influence of corticosteroids and prolactin
- 1 December 1983
- journal article
- research article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 99 (3), 465-468
- https://doi.org/10.1677/joe.0.0990465
Abstract
Evidence is presented that transcortin and α2u-globulin react as negative acute-phase proteins in the rat. Thirty-six hours after turpentine injection, the serum concentration of these proteins showed a two- to threefold decrease. Thereafter, transcortin rapidly returned to normal values, whereas α2u-globulin remained low. This reaction pattern was still present after adrenalectomy, adrenalectomy and administration of glucocorticoids, and after treatment with bromocriptine, a suppressor of prolactin secretion. It is concluded that changes in the secretion of glucocorticoids and prolactin are not required for the observed turpentine-induced decrease of transcortin and α2u-globulin.This publication has 3 references indexed in Scilit:
- Synthesis in Vitro of Corticosteroid-Binding Globulin from Rat Liver Messenger Ribonucleic Acid*Endocrinology, 1981
- RELATIONSHIP BETWEEN THE PITUITARY GLAND AND GONADAL STEROIDS: INVOLVEMENT OF A HYPOPHYSIAL FACTOR IN REDUCED α2u-GLOBULIN AND INCREASED TRANSCORTIN CONCENTRATIONS IN RAT SERUMJournal of Endocrinology, 1978
- PLASMA PROLACTIN IN UNDISTURBED CANNULATED MALE RATS; EFFECTS OF PERPHENAZINE, FREQUENT SAMPLING, STRESS AND CASTRATION PLUS OESTRONE TREATMENTActa Endocrinologica, 1977