Simple method for detecting penicillinase-producing Neisseria gonorrhoeae and Staphylococcus aureus.

Abstract

A filter paper acidometric test, using bromocresol purple as pH indicator, for detecting penicillinase-producing Neisseria gonorrhoeae (PPNG) and Staphylococcus aureus gave complete agreement with the chromogenic cephalosporin and rapid iodometric methods when performed on 300 strains of gonococci and 70 strains of Staph aureus. The test is cheap and simple and may be used to screen for penicillinase-producing strains of N gonorrhoeae and Staph aureus.