Tularemia was first recognized in California and is now known to be widespread in U. S. A. and in addition to affecting the rabbit is prevalent in 24 or more animals in America. These include the wild rabbit, coyote, beaver, skunk, raccoon, fox, rat, squirrel, woodchuck, sheep, meadow-mouse, horned-owl, pheasant, fish, muskrat, hog, lamb, dog, wood-tick, horsefly and other insects; water-borne infection has also been recognized. An account is given of 4 cases of ulceroglandular tularemia in individuals who had not handled rabbits or other game. 3 patients were infected by domestic cats, which scratched the hands of 2 and the face of a 3d; the 4th became ill after the bite of a wood tick. The 3 cats were examined; in 1 the serum agglutinated Pasteurella tularensis to 1:320; in another agglutinins were present in dilutions of 1:25-1:50 but no gross or microscopic lesions were observed post mortem; the 3d cat had neither agglutinins in its serum nor post mortem evidence of infection, but it hunted in nearby fields and was thought to have been contaminated but to have escaped infection. The susceptibility of the house-cat to infection with Past. tularensis has been demonstrated exptly. and the Public Health Bull, of Apr. 1940 reported a total of 13 persons with tularemia after contact with cats, 2 having been scratched and 11 having been bitten. House pets, such as cats, when kept in rural communities, may hunt in the fields and become contaminated or infected with Past. tularensis. Such a possible source for illness in man should not be overlooked.