Chemical synthesis of 2-O-(α-L-fucopyranosyl)-3-O-(2-acetamido-2-deoxy-α-D-galactopyranosyl)-D-galactose, the terminal structure in the blood-group A antigenic determinant

Abstract

The trisaccharide (1), the terminal structure in the blood-group A antigenic determinant, has been prepared from the trisaccharide (4) which was obtained from the product of a cycloaddition and seems to be a suitable precursor for synthesis of modified A and B blood-group antigens.