Limitations of the single sample tracer method for determining glomerular filtration rate
- 1 December 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in The British Journal of Radiology
- Vol. 51 (612), 981-985
- https://doi.org/10.1259/0007-1285-51-612-981
Abstract
Apparent volumes of distribution of 51Cr-EDTA and 99Tcm-DTPA [diethylene triamine pentaacetic acid] were calculated 3 h after i.v. injection and correlated with simultaneous estimation of GFR [glomerular filtration rate]. A reasonable correlation between these values was obtained for those patients with GFR > 50 ml/min (standard error of estimate using 51Cr-EDTA 7.6 ml/min and 99Tcm-DTPA 13.7 ml/min). Theoretical reasons are given why a single sample technique will not be accurate over a wide range of renal function.This publication has 5 references indexed in Scilit:
- Glomerular filtration rate estimation based on a single blood sample.BMJ, 1975
- MEASUREMENT OF GLOMERULAR FILTRATION-RATE IN MAN USING A 51Cr/EDETIC-ACID COMPLEXThe Lancet, 1967
- The Theory of Tracer Experiments with 131I-Labelled Plasma ProteinsPhysics in Medicine & Biology, 1957
- Volumes of Distribution and Clearances of Intravenously Injected Creatinine in the DogAmerican Journal of Physiology-Legacy Content, 1955
- THE MEASUREMENT OF THE TUBULAR EXCRETORY MASS, EFFECTIVE BLOOD FLOW AND FILTRATION RATE IN THE NORMAL HUMAN KIDNEYJCI Insight, 1938