Complementary addressed modification of double‐stranded DNA within a ternary complex
- 15 February 1988
- journal article
- Published by Wiley in FEBS Letters
- Vol. 228 (2), 273-276
- https://doi.org/10.1016/0014-5793(88)80014-0
Abstract
Double-stranded DNA containing a d(pG)18·d(pC)18 sequence was shown to be selectively alkylated in the vicinity of this fragment using the 5′-p-(N-2-chloroethyl-N-methylamino)benzylamide of deoxyribooligocytidylate, CIRCH2NH(pdC) n (n = 9, 15), in conditions favouring triple-stranded complex formation.Keywords
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