Nasojejunal feeding was used in 48 infants and found to be a practical and useful means of feeding premature and otherwise ill infants in whom conventional feeding was judged hazardous. A limp, polyvinyl tube with an outside diameter of 1.5 mm and a .9 mm bore was passed from the stomach through the pylorus. A tiny, reusable gold bead helped weight-direct the tip of the tube. Full enteral infant feeding can be accomplished nonsurgically for a period of weeks with less regurgitation, aspiration, and gastric distention than seen with gastric tube, gavage, or gastrostomy feeding. In order to avoid the potential dangers inherent in bypassing the pylorus, the need for close attention to the amount, the type, and, especially, the osmolarity of the jejunal feeding is stressed.