CONCERNING THE INCREASE IN CENTRAL VENOUS AND ARTERIAL BLOOD PRESSURES DURING CYCLO-PROPANE ANESTHESIA IN MAN

Abstract

In 15 healthy patients undergoing surgery, with cyclopropane anesthesia, the arterial and central venous pressures were recorded and the pH and CO2 tension of the arterial blood were measured. Control measurements were made in the resting subject before anesthesia induction. Care was taken to avoid hypoxia throughout the investigation. An increase in arterial pressure occurred in most cases and was greatest in subjects with respiratory acidosis. There was a consistent rise in venous pressure, greatest in those who developed increased CO2 tension. The rise in CO2 tension was directly related to rise in arterial blood cyclopropane. In most subjects cyclopropane caused a fall in pulse rate, more so if the central venous pressure was high. A sharp rise in arterial pressure and fall in venous pressure followed reduction of the inspired cyclopropane concn.