Dimetridazole, a Systemic Treatment for Bovine Venereal Trichomoniasis. I. Oral Administration

Abstract

Trichomonas foetus infections were eliminated from six bulls by the oral administration of dimetridazole at the rate of 50 mg/kg body weight daily for 5 consecutive days. The chemical was given either by capsule, or admixed with the feed. Five daily doses at 25 mg/kg administered by capsule freed another bull of T. foetus, but this level was ineffective when fed in grain to two bulls. One of the latter subsequently became negative after repeated courses of treatment at higher dosages. The other bull retained the infection.