Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine*
- 22 September 1997
- journal article
- research article
- Published by Wiley in Clinical Pharmacology & Therapeutics
- Vol. 62 (3), 248-260
- https://doi.org/10.1016/s0009-9236(97)90027-8
Abstract
Interpatient differences in the oral clearance of cyclosporine (INN, ciclosporin) have been partially attributed to variation in the activity of a single liver enzyme termed CYP3A4. Recently it has b...Keywords
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