IDIOTYPE EXPRESSION AND THE INHERITANCE OF MOUSE ANTIBODY CLONES
Open Access
- 1 March 1973
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 137 (3), 603-621
- https://doi.org/10.1084/jem.137.3.603
Abstract
The inheritance of idiotypes was investigated using idiotypic antisera against two monoclonal antibodies to streptococcal carbohydrates derived from A/J mice. Each of the two idiotypes was characterized by a special frequency of expression. One of the idiotypes was expressed in more than 80% of A/J mice, the other in less than 20%.Keywords
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