Prolonged Bleeding Time in Children and Young Adults with Hemophilia

Abstract

Of 49 patients with hemophilia A or B who had not received replacment transfusions for at least 72 h, 10 were demonstrated to have a prolonged value for the bleeding time. None had evidence of von Willebrand''s disease or prior aspirin ingestion, and only 1 had an associated intrinsic platelet defect. The bleeding time, generally thought to be a measurement of platelet-subendothelium interaction, may also sometimes be prolonged in congenital coagulation disorders in which platelet function is normal.