One hundred requests for predictive testing for Huntington's disease
- 28 June 1992
- journal article
- Published by Wiley in Clinical Genetics
- Vol. 41 (6), 326-330
- https://doi.org/10.1111/j.1399-0004.1992.tb03407.x
Abstract
In Grampian region, the first 100 requests for predictive testing for Huntington's disease have been analysed. Forty-five presymptomatic predictive test results have been given, eleven families have made a decision to undergo prenatal exclusion tests, and so far eleven pregnancies have been investigated using chorion villus biopsy. This paper presents the protocol used and a descriptive analysis of those receiving results, those choosing to leave the programme, and those unable to complete it because of an unsuitable family structure or unco-operative relatives.Keywords
This publication has 10 references indexed in Scilit:
- Genetic testing for Huntington's disease.BMJ, 1990
- The Prevalence and Patterns of Care of Huntington's Chorea in GrampianThe British Journal of Psychiatry, 1989
- UPTAKE OF PRESYMPTOMATIC PREDICTIVE TESTING FOR HUNTINGTON'S DISEASEThe Lancet, 1989
- A highly polymorphic locus very tightly linked to the Huntington's disease geneNature, 1988
- The dilemma of suicide and Huntington diseaseAmerican Journal of Medical Genetics, 1987
- Probes in Huntington's choreaNature, 1986
- Potential impact of a predictive test on the gene frequency of Huntington diseaseAmerican Journal of Medical Genetics, 1984
- A polymorphic DNA marker genetically linked to Huntington's diseaseNature, 1983
- Attitudes of subjects at risk and their relatives towards genetic counselling in Huntington's chorea.Journal of Medical Genetics, 1983
- Attitudes of families to some aspects of Huntington's choreaPsychological Medicine, 1979