Extensive Nodular Infiltration of Extra‐osseous Tissues in Human Myelomatosis

Abstract
The autopsy findings of a woman with myelomatosis diagnosed 6 mo. before her death are described. She had an IgG-.lambda. [immunoglobulin G-.lambda.] myeloma which initially responded to treatment. Subsequently she developed a condition characterized by massive soft tissue involvement with increased plasma cells in the peripheral blood. Rounded hard myeloma infiltrates were disseminated through the body, only sparing the adrenal glands and intracranial structures.