RENAL FUNCTION AS A FACTOR IN THE URINARY EXCRETION OF ASCORBIC ACID

Abstract
The effect of impaired kidney function on ascorbic acid excretion in man has been studied. Urinary ascorbic acid excretion tests are markedly affected in conditions involving functional renal disturbance, indicating an apparent sub-nutrition or deficiency which is referable to the altered kidney function and not to the ascorbic acid nutritional state. The effect of lowered kidney function on the ascorbic acid clearance runs parallel to the effect on the urea clearance.