c‐erbB‐3 protein expression in human breast cancer: comparison with other tumour variables and survival
- 1 September 1994
- journal article
- Published by Wiley in Histopathology
- Vol. 25 (3), 247-252
- https://doi.org/10.1111/j.1365-2559.1994.tb01324.x
Abstract
C‐erbB‐3 protein expression was investigated immunohistochemically in a series of 97 malignant breast tumours using the monoclonal antibody RTJ1. Twenty‐eight cases (28.8%) showed c‐erbB‐3 overexpression, 31 cases (32%) showed normal levels of c‐erbB‐3 and 38 cases (39.2%) were c‐erbB‐3 negative. c‐erbB‐3 overexpression was positively but not significantly related to negative lymph node status and survival over a 10‐year follow‐up period.Keywords
This publication has 16 references indexed in Scilit:
- Expression of the C‐erbB‐3 protein in gastrointestinal tract tumours determined by monoclonal antibody RTJ1The Journal of Pathology, 1993
- Expression of the ERBB3 gene product in breast cancerBritish Journal of Cancer, 1992
- TheerbB-3 Gene in human pancreatic cancerThe Journal of Pathology, 1992
- c-erbB-2 protein overexpression in breast cancer is a risk factor in patients with involved and uninvolved lymph nodesBritish Journal of Cancer, 1991
- c-erbB-2 oncoprotein expression in primary and advanced breast cancerBritish Journal of Cancer, 1991
- Molecular cloning and expression of an additional epidermal growth factor receptor-related gene.Proceedings of the National Academy of Sciences, 1990
- Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors.Proceedings of the National Academy of Sciences, 1989
- Pattern of expression of c-erbB-2 oncoprotein in human fetusesBritish Journal of Cancer, 1989
- Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu OncogeneScience, 1987
- Cellular localisation of human epidermal growth factor receptorCell Biology International Reports, 1984