Induction of melanogenesis in vitro in the epidermal melanoblasts of newborn mouse skin by MSH
- 1 May 1977
- journal article
- conference paper
- Published by Springer Nature in In Vitro Cellular & Developmental Biology - Plant
- Vol. 13 (5), 311-315
- https://doi.org/10.1007/bf02616177
Abstract
The number of epidermal melanocytes positive to the dopa reaction increased when skin explants from newborn mice were cultured with MSH or dbc-AMP. These agents seem to induce melanogenesis in the pre-existing melanoblasts. This hormone-induced melanogenesis is suppressed by actinomycin D or cycloheximide, suggesting that the initiation of melanogenesis in the epidermal melanoblasts requires de novo transcription and translation.This publication has 23 references indexed in Scilit:
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