The Effect of Adrenalectomy and Cortisone Supplementation on Caries Incidence in Caries-susceptible Rats
- 1 January 1965
- journal article
- research article
- Published by SAGE Publications in Journal of Dental Research
- Vol. 44 (1), 96-98
- https://doi.org/10.1177/00220345650440013701
Abstract
Caries-susceptible rats (112) were equally distributed among 5 groups by litter and sex as follows control, control + NaCl supplemented, adrenalectomized + NaCl supplemented, control + cortisone supplemented (0.6 mg/day) and adrenalectomized + cortisone supplemented (0.6 mg/day). Contrary to previous reports, adrenalectomy did not increase the caries susceptibility of caries-susceptible rats. Animals receiving salt supplementation of the diet and drink demonstrated a trend toward lower scores for third molars only. Intact rats receiving 0.6 mg cortisone/ day exhibited higher scores of boderline significance, which was not seen in adrenalectomized animals also receiving cortisone.Keywords
This publication has 4 references indexed in Scilit:
- Developmental and post-developmental influences on incidence of experimental dental caries resulting from dietary supplementation by various elementsArchives of Oral Biology, 1961
- Partial Substitution of Hexitols for Sucrose and Dextrin in Caries-producing DietsJournal of Dental Research, 1960
- The Development of Hypertension and Nephritis in Normal and Adrenalectomized Rats Treated With Cortisone.Experimental Biology and Medicine, 1949
- Dental Caries in the Cotton RatJournal of Nutrition, 1944