ON DOUBLE-MINUTES AND THEIR ORIGIN IN A BENIGN HUMAN NEOPLASM, A MIXED SALIVARY-GLAND TUMOR

  • 1 January 1982
    • journal article
    • research article
    • Vol. 2 (5), 261-264
Abstract
The cytogenetical observations in the 1st double-minute (DM)-positive benign neoplasm, a human pleomorphic adenoma, are described. In the present adenoma, the 1st DM was apparently formed from a structurally and/or functionally specialized segment of the long arm of a chromosome no. 12. If so, the results also indicate a close relation between chromosome regions preferentially involved in structural rearrangements in a certain tumor type and chromosome regions with the potential capacity to become released and behave and function as DM.