FAILURE OF BOMBESIN TO ALTER ANTERIOR PITUITARY HORMONE SECRETION IN MAN
- 1 October 1980
- journal article
- research article
- Published by Wiley in Clinical Endocrinology
- Vol. 13 (4), 369-373
- https://doi.org/10.1111/j.1365-2265.1980.tb03398.x
Abstract
Because of the stimulating effects of bombesin on growth hormone and prolactin secretion in the rat, we have studied the effects of bombesin infusions on anterior pituitary hormone secretion in man. Biological activity of the infused bombesin was confirmed by observing a brisk increase in serum gastrin concentrations and in gastric acid secretion during the lowest dose of bombesin infused. We could demonstrate no effect of bombesin in doses from 200 to 600 pmol.kg−1.h−1 on growth hormone, prolactin, thyrotrophin, luteinizing hormone and follicle stimulating hormone.This publication has 23 references indexed in Scilit:
- Cholecystokinin octapeptide releases growth hormone from the pituitaryLife Sciences, 1979
- Bombesin-like peptide in hypothalamus: Chemical and immunological characterizationLife Sciences, 1978
- Bombesin affects the central nervous system to produce hyperglycemia in ratsLife Sciences, 1977
- Thyrotropin-releasing hormone in the gastrointestinal tractBiochemical and Biophysical Research Communications, 1977
- GLUCAGON SECRETION INDUCED BY BOMBESIN IN MANThe Lancet, 1977
- Actions of bombesin, thyrotropin releasing factor, prostaglandin E2 and naloxone on thermoregulation in the ratLife Sciences, 1977
- ENKEPHALIN-LIKE IMMUNOREACTIVITY IN THE HUMAN GASTROINTESTINAL TRACTThe Lancet, 1977
- Vasoactive Intestinal Polypeptide: Abundant Immunoreactivity in Neural Cell Lines and Normal Nervous TissueScience, 1976
- DISTRIBUTION OF A BOMBESIN-LIKE PEPTIDE IN HUMAN GASTROINTESTINAL TRACTThe Lancet, 1976
- Somatostatin: Abundance of Immunoreactive Hormone in Rat Stomach and PancreasScience, 1975