Plasmodium falciparum-infected erythrocytes form spontaneous erythrocyte rosettes.
Open Access
- 1 May 1989
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 169 (5), 1835-1840
- https://doi.org/10.1084/jem.169.5.1835
Abstract
Erythrocytes infected with trophozoites or schizonts of Plasmodium falciparum bind uninfected erythrocytes, leading to rosette formation. Both established laboratory strains and fresh isolates from patients form such rosettes, but at widely different frequencies. IgG preparations from the serum of some P. falciparum-immune donors and heparin inhibited rosette formation. The results indicate that cytoadherence of infected erythrocytes to endothelial cells and rosetting represent distinct genetic traits.This publication has 6 references indexed in Scilit:
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