Cerebral Hyponatremia

Abstract

WHEN water retention is induced in a normal person by the administration of exogenous antidiuretic hormone, the serum sodium falls, and the renal excretion of sodium increases.¹ Inappropriate release of endogenous vasopressin has been suggested as the cause of hyponatremia and renal salt wasting in certain diseases, including bronchogenic carcinoma,^{2 3 4} cerebral injuries^{5 , 6} and malformations⁷; it is probably also responsible for hyponatremia in tuberculous meningitis.^{8 , 9} Inability to excrete water normally is also a feature of the salt wasting of certain hyponatremic patients with pulmonary tuberculosis.¹⁰ The present report concerns a young woman in whom chronic hyponatremia was associated over a . . .