Cultivation of Enteroviruses in Hamster Kidney Tissue Culture

Abstract
Susceptibility of hamster kidney tissue culture to enteroviruses was studied. A cytopathogenic effect was obtained with the prototype Coxsackie viruses (A9, B1–B5) and prototype ECHO virus types 9 and 10. Variability of infectivity was shown for ECHO 9 isolates, only 2 of 27 positive. Other ECHO serotypes and polioviruses were negative. Strains of herpes simplex, vaccinia, Newcastle disease virus and influenza (Asian), also produced a cytopathogenic effect in hamster kidneys. Use of hamster kidney tissue cultures as a selective system in identification of agents from cases of aseptic meningitis was reported.