Fortimicins A and B, new aminoglycoside antibiotics. I. Producing organism, fermentation a biological properties of fortimicins.
- 1 January 1977
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 30 (7), 533-540
- https://doi.org/10.7164/antibiotics.30.533
Abstract
A culture of Micromonospora sp. MK-70 produced 2 new antibiotics, fortimicins A and B. Antibacterial and paper chromatographic data on an eluate from IRC-50 treatment of fermentation beers indicated that fortimicins A and B are new antibiotics with broad-spectrum, basic and water-soluble properties. Fortimicin A exhibited potent, unique, broad-spectrum antibacterial activity against gram-positive and negative bacteria in vitro and in vivo, while fortimicin B was only weakly active.This publication has 1 reference indexed in Scilit:
- A new aminoglycoside antibiotic complex - The seldomycins. IV. The structure of seldomycin factor 5.The Journal of Antibiotics, 1977