A case of chronic meningitis, fatal after 11 months, is described. In addition to the clinical features often present in chronic meningitis, other findings included a predominance of neutrophils in the cerebrospinal fluid, adhesions across the ventricles demonstrated by pneumoencephalography, and obstruction of the internal carotid artery in the supraclinoid portion. At autopsy, infection was determined to be caused by the fungus, Cladosporium trichoides. No portal for the infection was found. Although this was an unusual manifestation of the disease, review of the literature suggests that cerebral dematiomycosis embraces a spectrum in which symptoms of either brain abscess or chronic meningitis may predominate.