THE BIOLOGICAL ACTIVITY OF O-METHYL THYROXINE1
- 1 November 1955
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 57 (5), 566-570
- https://doi.org/10.1210/endo-57-5-566
Abstract
O-Methyl-DL-thyroxine was approximately twice as active as DL-thyroxine in causing tail shrinkage in R. clamitans tadpoles. It was 1/3 as effective as DL-thyroxine in stimulating O2 consumption of rats but was only slightly active in preventing thyroid enlargement of thiouracil-fed rats. Thiouracil feeding did not prevent the effect of O-methyl thyroxine on basal metabolic rate of rats.Keywords
This publication has 6 references indexed in Scilit:
- DETERMINATION OF THE OXYGEN CONSUMPTION OF GROUPS OF RATSEndocrinology, 1955
- THE THYROXINE-LIKE ACTIVITY OF SOME NEW THYROXINE ANALOGUES IN AMPHIBIAJournal of Biological Chemistry, 1954
- The biological action of substances related to thyroxine. 7. The metabolism of butyl 4-hydroxy-3:5-diiodobenzoateBiochemical Journal, 1954
- THE PHYSIOLOGIC ACTIVITY OF SOME ANALOGUES OF THYROXINE*Journal of Clinical Endocrinology & Metabolism, 1952
- THE THYROXINE-LIKE ACTIVITY OF COMPOUNDS STRUCTURALLY RELATED TO THYROXINEJournal of Biological Chemistry, 1948
- A DETERMINATION OF THE RATE OF THYROID HORMONE SECRETION AT VARIOUS ENVIRONMENTAL TEMPERATURES1Endocrinology, 1943