Isolated Adrenal Cortex Cells: Hypersensitivity to Adrenocorticotropic Hormone after Hypophysectomy
- 30 March 1973
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 179 (4080), 1330-1331
- https://doi.org/10.1126/science.179.4080.1330
Abstract
Cells from the adrenals of hypophysectomized rats (up to 28 days after operation) require less adrenocorticotropic hormone to induce one-half maximal rate of production of 3',5'-adenosine monophosphate than do cells from the adrenals of intact rats. A corresponding increase in sensitivity is reflected in the steroidogenic response to adrenocorticotropic hormone up to 2 days after hypophysectomy.Keywords
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