Bactericidal Activity of Streptomycin and Isoniazid in Combination with p-Aminosalicylic Acid against Mycobacterium tuberculosis
- 1 February 1955
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 12 (1), 76-84
- https://doi.org/10.1099/00221287-12-1-76
Abstract
P-Aminosalicylic acid (PAS) partially inhibits the growth of Mycobacterium tuberculosis, but is less effective alone than either streptomycin or isoniazid. At low concentrations, little effect is observed by the addition of PAS. At high concentrations of streptomycin, isoniazid, or both, addition of PAS increases the bactericidal effect, and resistant forms are entirely suppressed.Keywords
This publication has 4 references indexed in Scilit:
- In vitro Effect of Streptomycin and Para-Aminosalicylic Acid (PAS) on the Growth of Tubercle Bacilli.Experimental Biology and Medicine, 1948
- THE ACTION OF P-AMINOSALICYLIC ACID (PAS) IN EXPERIMENTAL TUBERCULOSIS1948
- TREATMENT OF EXPERIMENTAL TUBERCULOSIS IN MICE AND GUINEA-PIGS WITH PARA-AMINOSALICYLIC ACID (PAS) AND STREPTOMYCIN1948
- PARA-AMINOSALICYLIC ACID IN THE TREATMENT OF TUBERCULOSISThe Lancet, 1946