Ultraschallgeschwindigkeitsmessung zur Diagnose der postmenopausalen Osteoporose

Abstract

We evaluated ultrasound transmission velocity as an indicator for osteoporosis at the os calcis of both feet and at the proximal phalanges of DII and DIII of both hands in 74 female subjects (22 premenopausal, 29 postmenopausal non-osteoporotic and 23 postmenopausal osteoporotic). In addition dual x-ray absorptiometry (DXA) of the lumbar spine was performed in 30 women and a combined cortical thickness index (CCT-index) of os metacarpale II was calculated from hand radiographs in 29 women. Ultrasound velocity at all sites slightly decreased in premenopausal women with age and declined significantly after menopause. At the hand postmenopausal osteoporotic women had significantly lower velocities than normal postmenopausal or premenopausal women while no difference could be seen at os calcis. An only poor or moderate correlation between ultrasound velocity at all sites and DXA of the lumbar spine and a good correlation between the CCT-index and velocity at the fingers indicate that ultrasound velocity is not only affected by bone density but even more by structural properties.