Unusual features of protein interaction in human immunodeficiency virus (HIV) virions
- 1 September 1990
- journal article
- conference paper
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 110 (3-4), 287-293
- https://doi.org/10.1007/bf01311297
Abstract
The treatment of HIV-1 virions with ionic and nonionic detergents (NP 40, ocytlglucoside, Na deoxycholate) resulted in an effect unusual for enveloped viruses: instead of solubilization of glycoproteins, the core protein p24 was solubilized while envelope glycoproteins with other structural proteins were found in subviral particles. These date are consistent with a model of HIV structural organization in which glycoproteins are included in the matrix formed by the protein p17 and suggest that p24 is neither involved in the matrix nor closely bound to any viral proteins.Keywords
This publication has 27 references indexed in Scilit:
- The morphology of human immunodeficiency virus (HIV) by negative stainingJournal of Medical Virology, 1988
- Fine structure of human immunodeficiency virus (HIV), immunolocalization of structural proteins and virus-cell relationMicron and Microscopica Acta, 1988
- The T=4 envelope of sindbis virus is organized by interactions with a complementary T=3 capsidCell, 1987
- Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteinsVirology, 1987
- Influenza Virus Uncoating in Infected Cells and Effect of RimantadineJournal of General Virology, 1982
- Penetration of Viral Genetic Material into Host CellPublished by Elsevier ,1982
- Electrophoretic Separation of Influenza Virus RibonucleoproteinsJournal of General Virology, 1981
- The Interaction of Influenza Virus Haemagglutinin with Phospholipid Vesicles -- Morphological and Immunological StudiesJournal of General Virology, 1981
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970