Proteolytic cleavage of bacteriophage lambda repressor in induction.
- 1 January 1975
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 72 (1), 147-151
- https://doi.org/10.1073/pnas.72.1.147
Abstract
The bacteriophage lambda repressor, a protein that maintains the lysogenic state of a bacterium containing a lambda prophage, is cleaved when the lysogen is induced by mitomycin C or ultraviolet light. This cleavage does not occur when induction is prevented by mutational alteration either of the phage repressor or of the host recA gene product. Proteolytic cleavage may be the primary mechanism of repressor inactivation in this induction pathway, or it may follow a different event which causes the initial inactivation.Keywords
This publication has 18 references indexed in Scilit:
- Thermal Enhancement of Ultraviolet Mutability in a tif-1 uvrA Derivative of Escherichia coli B/r: Evidence That Ultraviolet Mutagenesis Depends upon an Inducible FunctionProceedings of the National Academy of Sciences, 1974
- RECOMBINATION DEFICIENT MUTANTS OF E. COLI AND OTHER BACTERIAAnnual Review of Genetics, 1973
- Genetic analysis of the recF pathway to genetic recombination in Escherichia coli k12: Isolation and characterization of mutantsJournal of Molecular Biology, 1973
- Mitochondrial assembly in respiration-deficient mutants of Saccharomyces cerevisiae. II. Effect of nuclear and extrachromosomal mutations on the formation of cytochrome c oxidase.1973
- Lysogenic InductionProgress in Nucleic Acid Research and Molecular Biology, 1973
- Inactivation kinetics of Lambda phage repressors in a mutant of E. coli temperature sensitive in DNA replicationMolecular Genetics and Genomics, 1972
- Control of λ Repressor SynthesisProceedings of the National Academy of Sciences, 1971
- ISOLATION OF THE λ PHAGE REPRESSORProceedings of the National Academy of Sciences, 1967
- Effect of ultraviolet irradiation on bacteriophage lambda immunityJournal of Molecular Biology, 1967
- [System of repression insuring immunity in lysogenic bacteria].1959