LIVER-ABSCESS AT THE HADASSAH UNIVERSITY HOSPITAL DURING THE YEARS 1967-77

Abstract

The charts of 36 patients, 27 males and 9 females with liver abscess diagnosed at the Hadassah University Hospital between 1967-1977 were reviewed. The patients ranged in age from 2 mo.-80 yr, and 25 patients (69%) were older than 40 yr. The diagnosis was initially suggested by liver scan in 18 patients (50%) and was 1st made at autopsy in 6 (17%). The time lapse between the onset of illness and diagnosis ranged from 1 day to 13 mo., with a bimodal distribution. Large solitary abscesses were diagnosed later than small multiple abscesses. Ten patients (28%) were admitted with fever as the only sign of illness; specific signs and laboratory evidence of liver involvement often occurred late in the course of the disease. In 15 patients (42%), the etiology was regarded as amebic. In patients with pyogenic abscesses the most commonly isolated organisms belonged to the normal bowel flora, and biliary tract disease was present in 62% (13/21) of these patients. The overall mortality rate was 31%. The need for an increased awareness of the subtle presentation of liver abscess is stressed.