Genetic variants of glucose phosphate isomerase (E.C. 5.3.1.9) in canine erythrocytes*

Abstract

Genetic polymorphism of glucose phosphate isomerase (GPI) was found in the erythrocytes of dogs of 6 Japanese breeds by using starch gel electrophoresis. Analysis of parentage records of dogs revealed that the phenotypic variation of erythrocyte GPI was controlled by 1 autosomal locus with 2 codominant alleles, GPIA and GPIB. The allele GPIB was observed in the following breeds: San''in-Shiba, Shinshu-Shiba, Shikoku, Kai and Kishu, but not in Hokkaidoes and Akitas. All the dogs belonging to 25 European breeds and 5 oriental (except Japan) or Chinese breeds examined in this experiment had the genotype GPIA/GPIA, whereas 1 Dalmatian dog was heterozygous GPIA/GPIB.