Hemolytic Uremic Syndrome
- 8 March 1965
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 191 (10), 787-792
- https://doi.org/10.1001/jama.1965.03080100005001
Abstract
In six infants and children, acute renal failure, following diarrhea, was associated with hemolytic anemia and thrombocytopenia. This combination of findings, referred to as the hemolytic uremic syndrome, has been recognized with increasing frequency. Four of six patients died despite treatment by transfusion and dialysis. The pathological findings were not uniform and included glomerulonephritis, thrombotic thrombocytopenic purpura, and renal cortical necrosis. The etiology remains obscure. Available evidence suggests that a hypersensitivity process is involved in the pathogenesis.Keywords
This publication has 3 references indexed in Scilit:
- Microangiopathic Haemolytic Anaemia: The Possible Role of Vascular Lesions in PathogenesisBritish Journal of Haematology, 1962
- A Haemolytic-uraemic Syndrome in InfancyArchives of Disease in Childhood, 1961
- ALTERATIONS IN THE BLOOD COAGULATION SYSTEM INDUCED BY BACTERIAL ENDOTOXINThe Journal of Experimental Medicine, 1958