SQUAMOUS CELL CARCINOMA OF THE RENAL PELVIS ASSOCIATED WITH STONE AND LEUKOPLAKIA

Abstract

The following case is reported because it represents from a clinical and pathologic standpoint the various stages in the development of a squamous cell carcinoma of the renal pelvis. Reports of similar cases, although not frequent, illustrate the important relation of irritation¹ to leukoplakia, and of continued irritation to consequent carcinomatous changes. Kutmann^1a reported a case of leukoplakia in the renal pelvis, and stated that only 67 similar unquestioned cases had been reported. Patch² found reports of 152 cases of squamous cell carcinoma in the urinary tract; 36 renal, 6 ureteral and 10 vesical. In 13 cases, cancer and leukoplakia coexisted. Equally interesting is the relation of calculi to the development of squamous cell tumors. Wells³ in 1922 found reports of 11 unquestioned cases of squamous cell cancer of the renal pelvis, and reported a case of his own. The presence of calculi was mentioned in