Breast carcinoma following radiotherapy of metastatic Wilms' tumor

Abstract
A 22‐year‐old woman developed breast cancer 15 years after radiotherapy to the lung for metastatic Wilms' tumor. Her 32‐year‐old mother died of bilateral breast cancer, suggesting a genetic predisposition to radiogenic cancer. Recent improvements in the survival of children with certain cancers necessitate long‐term surveillance for iatrogenic neoplasia, particularly when familial susceptibility is evident.