The association of lesions of the fundus with hypertensive vascular diseases has been the subject of many papers during the past few years. The clinical significance of this association and its varied interpretation by internists, pathologists and ophthalmologists warrant further investigations and reports in order that the correlation may be better understood. For an intelligent interpretation of lesions of the fundus observed in cases of hypertensive vascular disease, information is necessary concerning the onset of hypertension, i. e., whether it is mild and gradual, extending over a long period, or acute and accelerated ; the systolic and diastolic blood pressure readings; the results of urinalysis and studies of the blood chemistry ; the presence of persistent headaches, nausea and visual disturbances, and a history of hereditary hypertension. The lesions may be stationary, progressive or retrogressive, or there may be remissions, depending on the degree and consistency of elevation of the systolic and