Genetic Features of the Widespread Plasmid Coding for the Carbapenemase OXA-48
Top Cited Papers
- 1 January 2012
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 56 (1), 559-562
- https://doi.org/10.1128/aac.05289-11
Abstract
Complete sequencing of plasmid pOXA-48a carrying the bla(OXA-48) gene from a Klebsiella pneumoniae isolate was performed. Its backbone corresponded to that of an IncL/M-type plasmid, in which the bla(OXA-48) gene had been integrated through the acquisition of the Tn1999 composite transposon without any other antibiotic resistance gene. Molecular epidemiology using a collection of international OXA-48 producers revealed the wide diffusion of pOXA-48a or closely related plasmids.Keywords
This publication has 28 references indexed in Scilit:
- Resistance Plasmid Families in EnterobacteriaceaeAntimicrobial Agents and Chemotherapy, 2009
- Oxacillinase-mediated resistance to carbapenems in Klebsiella pneumoniae from LebanonClinical Microbiology & Infection, 2008
- Spread of OXA-48-Positive Carbapenem-Resistant Klebsiella pneumoniae Isolates in Istanbul, TurkeyAntimicrobial Agents and Chemotherapy, 2008
- Complete Nucleotide Sequence of the pCTX-M3 Plasmid and Its Involvement in Spread of the Extended-Spectrum β-Lactamase GeneblaCTX-M-3Antimicrobial Agents and Chemotherapy, 2007
- Carbapenemases: Molecular Diversity and Clinical ConsequencesFuture Microbiology, 2007
- Functional Characterization of IS 1999 , an IS 4 Family Element Involved in Mobilization and Expression of β-Lactam Resistance GenesJournal of Bacteriology, 2006
- A 10-min method for preparation of highly electrocompetent Pseudomonas aeruginosa cells: Application for DNA fragment transfer between chromosomes and plasmid transformationJournal of Microbiological Methods, 2005
- Identification of plasmids by PCR-based replicon typingJournal of Microbiological Methods, 2005
- Genome sequence of the dissimilatory metal ion–reducing bacterium Shewanella oneidensisNature Biotechnology, 2002
- Factors affecting the isolation of CCC DNA from Streptomyces lividans and Escherichia coliPlasmid, 1984