The synthesis and biological activity of (±)-(1α,2α,8α)-Indolizidine-1,2-diol

Abstract
The racemic indolizidine-1,2-dio1 (6) was synthesized and found to be a weak, in vitro inhibitor of acid α-D-mannosidase (Km 0.75 × 10-2) and acid α-D-glucosidase (Km 1.1 × 10-2 M).