TGF- β signaling in cancer – a double-edged sword
Top Cited Papers
- 1 November 2001
- journal article
- review article
- Published by Elsevier in Trends in Cell Biology
- Vol. 11 (11), S44-S51
- https://doi.org/10.1016/s0962-8924(01)02130-4
Abstract
No abstract availableKeywords
This publication has 66 references indexed in Scilit:
- Blockade of Smad4 in transformed keratinocytes containing a Ras oncogene leads to hyperactivation of the Ras-dependent Erk signalling pathway associated with progression to undifferentiated carcinomasOncogene, 2000
- Involvement of the Ras/MAPK Signaling Pathway in the Modulation of Urokinase Production and Cellular Invasiveness by Transforming Growth Factor-β1 in Transformed KeratinocytesBiochemical and Biophysical Research Communications, 2000
- A role for Smad6 in development and homeostasis of the cardiovascular systemNature Genetics, 2000
- Targeted Disruption in Murine Cells Reveals Variable Requirement for Smad4 in Transforming Growth Factor β-related SignalingPublished by Elsevier ,2000
- Smad4/DPC4 Silencing and Hyperactive Ras Jointly Disrupt Transforming Growth Factor-β Antiproliferative Responses in Colon Cancer CellsJournal of Biological Chemistry, 1999
- A mechanism of repression of TGFbeta / Smad signaling by oncogenic RasGenes & Development, 1999
- TGFβ signaling is necessary for carcinoma cell invasiveness and metastasisCurrent Biology, 1998
- Anti-transforming growth factor (TGF)-beta antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer cell activity. Implications for a possible role of tumor cell/host TGF-beta interactions in human breast cancer progression.Journal of Clinical Investigation, 1993
- Transforming growth factor β1 is implicated in the failure of tamoxifen therapy in human breast cancerBritish Journal of Cancer, 1991
- Mutation and Cancer: Statistical Study of RetinoblastomaProceedings of the National Academy of Sciences, 1971