TUMOR-LOCALIZING COMPONENTS OF THE PORPHYRIN PREPARATION HEMATOPORPHYRIN DERIVATIVE
- 1 January 1983
- journal article
- research article
- Vol. 43 (5), 1994-1999
Abstract
The tumor-localizing components of the porphyrin preparation, hematoporphyrin derivative, were characterized using aqueous and nonaqueous gel exclusion and reverse-phase chromatography. Localization is mediated by hematoporphyrin derivative components which are among the most hydrophobic in the preparation. This apparent hydrophobicity may derive from hydrogen-bonding phenomena, rather than from absence of hydrophilic functional groups. [Hematoporphyrin derivative is a radiosensitizer useful in treating cancer.].This publication has 21 references indexed in Scilit:
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