Amino‐Acid Sequence of the Vitamin‐K‐Dependent Part of Protein Z
Open Access
- 1 August 1982
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 126 (2), 343-348
- https://doi.org/10.1111/j.1432-1033.1982.tb06784.x
Abstract
After tryptic digestion of protein Z a peptide corresponding to residues 1-43 was isolated and sequenced. Smaller peptides were generated by treatment of the peptide with pepsin and then separated by high-performance liquid chromatography. The purity of the peptides was sufficient for mass spectrometric measurement. Thirteen .gamma.-carboxyglutamic acid residues were identified and the peptide shows strong homology to the corresponding domains of the classical vitamin-K-dependent blood clotting proteins.This publication has 26 references indexed in Scilit:
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