Nonoliguric Acute Renal Failure Associated with a Low Fractional Excretion of Sodium

Abstract

Measurement of the fractional excretion of Na was recommended as a useful clinical tool in evaluating acute renal failure. Six patients with nonoliguric acute renal failure had a fractional excretion of Na < 1.0%; these patients had severe liver dysfunction, which suggested a Na-acid state. A review of the literature showed that in patients with other Na-avid states (congestive heart failure, nephrotic syndrome and burns) the fractional excretion of Na was frequently .ltoreq. 1.0%. The fractional excretion of Na is a less useful diagnostic test in patients whose clinical state makes them Na avid.